Warfarin Research Paper

Warfarin Research Paper-10
A higher mean knowledge about warfarin score was found after counselling as compared to before counselling (4.82 vs 13.2; p Vitamin K antagonists, namely warfarin, remain one of the main oral anticoagulant treatments used for the prevention and treatment of cardiac, thromboembolic and hypercoagulable diseases [1,2,3,4].

A higher mean knowledge about warfarin score was found after counselling as compared to before counselling (4.82 vs 13.2; p Vitamin K antagonists, namely warfarin, remain one of the main oral anticoagulant treatments used for the prevention and treatment of cardiac, thromboembolic and hypercoagulable diseases [1,2,3,4].

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As part of the effective anticoagulation management, frequent INR monitoring, dose alteration, and patient’s education are also necessary.

Therefore, a health care professional (clinical pharmacist or physician) provided an oral counselling session for the patients to raise their level of awareness after the baseline assessment.

Monitoring the International Normalized Ratio (INR) is mandatory to optimize patient outcomes and minimize the risk of thrombosis, without increasing the risk of bleeding complications [5,6,7].

In fact, previous studies revealed that warfarin adverse reactions were responsible for considerable hospital admissions [8, 9].

Fib), valve disease/replacement, stroke or Systolic Left Ventricular Dysfunction (SLVD) were enrolled in this study.

Excluded from the analysis were patients who could not answer the questionnaire adequately either due to a decreased mental alertness or decreased cognitive function (cognitive disorders, sedated patients, Alzheimer’s disease, etc.).Health care professionals (HCP) are known key elements of effective patient’s counselling and education.For patients taking warfarin, education about the dose, side effects, and toxicity is clearly identified as a cornerstone of achieving improved health and quality of life.This survey was designed by two clinical pharmacists based on existing documents that took into account education and counselling of warfarin therapy provided to patients during their hospital discharge (Additional file 1) [23,24,25].An INR between 2 and 3 for all indications except for mitral valve replacement (INR range: 2.5-3.5) was considered as an adequate anticoagulation control [26].The questionnaire was administered face-to-face by trained researchers, who had a training prior to the start of the data collection to ensure the quality of research.Participants who were on warfarin for any of its approved indications (venous thromboembolism (VTE), atrial fibrillation (A.The duration of warfarin therapy since the patient started the treatment was divided into 4 categories (2-3 months, 4-6 months, 7-12 months and more than a year) [2].Furthermore, we assessed patients’ knowledge about warfarin and INR level recording (baseline) before the clinical pharmacist/physician counselling.Patients’ warfarin knowledge and INR levels were assessed before and after the clinical pharmacist counselling.The main therapeutic outcome was the impact of the clinical pharmacist-physician counselling on improving patient’s education and achieving therapeutic INR level.

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