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Recent clinical trials have indicated that immune checkpoint blockade (ICB) therapy, which is designed to unleash a patient's immune system to attack cancer, has been revolutionary in its implications for breast cancer treatment, ...

doi:10.7150/ijms.35083 [Abstract] [Full text] [PDF]Research Paper Elevated plasma S100A1 level is a risk factor for ST-segment elevation myocardial infarction and associated with post-infarction cardiac function Linlin Fan, Baoxin Liu, Rong Guo, Jiachen Luo, Hongqiang Li, Zhiqiang Li, Weigang Xu Int.

doi:10.7150/ijms.35037 [Abstract] [Full text] [PDF]Research Paper MRC-5 Cancer-associated Fibroblasts Influence Production of Cancer Stem Cell Markers and Inflammation-associated Cell Surface Molecules, in Liver Cancer Cell Lines Song-Ming Ding, Jian-Fang Lu, Muhammad Ibrahim Alhadi Edoo, Lin Zhou, Hai-Yang Xie, Shu-Sen Zheng, Qi-Yong Li Int.

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doi:10.7150/ijms.34758 [Abstract] [Full text] [PDF]Research Paper The phenotype of vascular smooth muscle cells co-cultured with endothelial cells is modulated by PDGFR-β/IQGAP1 signaling in LPS-induced intravascular injury Xia Zheng, Xiaotong Hu, Wang Zhang Int.

doi:10.7150/ijms.34749 [Abstract] [Full text] [PDF]Research Paper Expression pattern of CDK12 protein in gastric cancer and its positive correlation with CD8 cell density and CCL12 expression Jun Ji, Chenfei Zhou, Junwei Wu, Qu Cai, Min Shi, Huan Zhang, Yingyan Yu, Zhenggang Zhu, Jun Zhang Int. All three have published their work and findings ... Medical research Twenty people die every day waiting for an organ transplant in the United States, and while more than 30,000 transplants are now performed annually, there are over 113,000 patients currently on organ waitlists. Three separate and independent teams of researchers have attempted to replicate the results of a team which, back in 2016, claimed to have cured monkeys of an HIV-like infection. The medicinal application of mushrooms has been used in traditional medicine in many oriental countries. doi:10.7150/ijms.34386 [Abstract] [Full text] [PDF]Research Paper High mobility group box 1 protein (HMGB1) as biomarker in hypoxia-induced persistent pulmonary hypertension of the newborn: a clinical and in vivo pilot study Zhen Tang, Min Jiang, Zhicui Ou-yang, Hailan Wu, Shixiao Dong, Mingyan Hei Int. ...details Colorectal cancer (CRC) is one of leading causes of mortality in western countries and novel treatment strategies are required. doi:10.7150/ijms.34541 [Abstract] [Full text] [PDF]Research Paper Ribosomal Protein L15 is involved in Colon Carcinogenesis Zhixiong Dong, Hongyu Jiang, Shuangshuang Liang, Yajie Wang, Wei Jiang, Changjun Zhu Int. In the present study, we have developed polysaccharide-rich extracts from effects were determined by cytotoxicity assay, proliferation assay, wound healing assay and invasion assay. Polysaccharide-rich extracts obtained from certain medicinal mushroom species have shown antitumor effects in different experimental models. doi:10.7150/ijms.34073 [Abstract] [Full text] [PDF]Research Paper Parvalbumin Promoter Methylation Altered in Major Depressive Disorder Benjamard Thaweethee-Sukjai, Sirijit Suttajit, Samur Thanoi, Caroline F. doi:10.7150/ijms.36131 [Abstract] [Full text] [PDF]Research Paper The impact of PRDX4 and the EGFR mutation status on cellular proliferation in lung adenocarcinoma Kenichi Mizutani, Xin Guo, Akihiro Shioya, Jing Zhang, Jianbo Zheng, Nozomu Kurose, Hiroaki Ishibashi, Nozomu Motono, Hidetaka Uramoto, Sohsuke Yamada Int. It seems to happen almost every day - you hear about the results of a new medical research study.Sometimes the results of one study seem to disagree with the results of another study.


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