Asthma Research Papers

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Objective: To assess the effects of family structure on the treatment and outcomes of children with asthma.

Methods: Our data sources were the 1996-2003 Medical Expenditure Panel Survey (MEPS) and the 2003 National Survey of Children's Health (NSCH).

The use of a LABA, combined with an ICS, is a mainstay of treatment for patients with moderate to severe asthma.

Long-acting β-agonists should be used only in combination with ICSs, as indicated by the FDA “black box” warning pointing out that using LABAs alone carries the increased risks of worsening asthma and asthma-related deaths.

The study samples consisted of children 2-17 years of age with asthma who lived in single-mother or two-parent families.

We assessed the effect of number of parents and number of other children in the household on office visits for asthma and use of asthma medications using negative binomial regression, and we assessed the effect of family structure on the severity of asthma symptoms using binary and ordinal logistic regression.It is an indirect marker of eosinophilic airway inflammation.Patients with asthma or active inflammation have higher levels of Fe NO than do patients without asthma.Previously, use of inhaled anticholinergic agents had been reserved for treatment of patients with acute asthma exacerbations, and the only approved long-acting anticholinergic agent has been used primarily for the treatment of patients with chronic obstructive pulmonary disease (COPD).In an article published in reported results of the addition of the long-acting anticholinergic bronchodilator tiotropium bromide to an inhaled glucocorticoid in patients with inadequately controlled asthma.Currently there is a black box warning issued by the FDA regarding this practice.All these agents carry similar warnings and have similar efficacy in the treatment of patients with asthma or COPD, though there are important pharmacokinetic differences between them.The CDC further found that only 34.2% of persons with asthma reported that they had been given a written action plan by their health–care providers, and 68.1% of persons with asthma said they had been educated on the proper steps to take during an asthma attack.There have been advances in the diagnostic evaluation of patients suspected of having asthma.The normal range of Fe NO is 0 to 20 parts per billion.Levels of Fe NO higher than 35 parts per billion would be consistent with active eosinophilic inflammation, though atopic individuals generally tend to have higher Fe NO levels.


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